Consensus and conflict cards for metabolic pathway databases
نویسندگان
چکیده
منابع مشابه
Analysis and Comparison of Metabolic Pathway Databases
Enormous amounts of data result from genome sequencing projects and new experimental methods. Within this tremendous amount of genomic data 30-40 per cent of the genes being identified in an organism remain unknown in terms of their biological function. As a consequence of this lack of information the overall schema of all the biological functions occurring in a specific organism cannot be prop...
متن کاملMetaCyc and AraCyc. Metabolic pathway databases for plant research.
MetaCyc (http://metacyc.org) contains experimentally determined biochemical pathways to be used as a reference database for metabolism. In conjunction with the Pathway Tools software, MetaCyc can be used to computationally predict the metabolic pathway complement of an annotated genome. To increase the breadth of pathways and enzymes, more than 60 plant-specific pathways have been added or upda...
متن کاملEfficient Validation of Metabolic Pathway Databases
Metabolic pathway databases such as KEGG contain information on thousands of enzymatic reactions drawn from the biomedical literature. Ensuring consistency of such large metabolic pathways is essential to their proper use. In this paper, we develop an efficient method to determine consistency of an important class of enzymatic reactions, and test the method on the latest release of the KEGG LIG...
متن کاملPathway analysis in metabolic databases via differetial metabolic display (DMD)
MOTIVATION A number of metabolic databases are available electronically, some with features for querying and visualizing metabolic pathways and regulatory networks. We present a unifying, systematic approach based on PETRI nets for storing, displaying, comparing, searching and simulating such nets from a number of different sources. RESULTS Information from each data source is extracted and c...
متن کاملConflict Resolution in Online Databases*
Shared online databases, such as Google Fusion Tables or Quickbase, allow non-programmer community members to collaboratively maintain and browse data. While community members may believe in conflicting facts (due to conflicting sources, measurements or opinions), current online databases do not yet offer support for the management of data conflicts. Ricolla is a novel online database that trea...
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ژورنال
عنوان ژورنال: BMC Systems Biology
سال: 2013
ISSN: 1752-0509
DOI: 10.1186/1752-0509-7-50